I've been running ACKS since early summer, and it finally occurred to me to mention it in the Actual Play forum!
I started out well over a year ago with two competing ideas - Dwimmermount (pretty much vanilla, inasmuch as it's possible to describe Dwimmermount as 'vanilla') and a desire to create a campaign setting based on Gnostic mythology (absent supernal Creator vs relatively petty and venal Demiurge, the whole premise of gnosis, and historical connections to alchemical concepts). Eventually I decided to create a Gnostic-tinted world into which I could plug Dwimmermount with some changes here and there. Things were pretty much set, and I got ready to run the campaign...
Then I got hold of Sinister Stone of Sakkara, and my plans all changed again :) I really should get better at sticking to a single tone but the adventure was just too good to pass up, so I went back to the drawing board again, and started work on a setting where Dwimmermount would be higher-level material (on the other side of a mini-continent, within a vast alchemically-poisoned wasteland) while I figured out how to tweak the Sinister Stone into my existing setting, in which the "falling Empire" has fallen significantly more quickly than in the Auran Empire setting.
Eventually I ended up with Azoth Chronicles; a setting in which a succession of large, powerful empires have ruled the mini-continent and sponsored many many alchemists in plumbing the secrets of the elements. I added a quasi-Buddhist religious system inspired a little by the Elder Scrolls series (using formerly-mortal Bodhisattvas known as Ascendants rather than Gods in the usual sense, acting as conduits through which Clerics can touch the Supernal, transcendant reality outside the corrupt physical world), set up a pile of potential national-scale conflicts, and picked a suitable location to put the Temple of the Stone - which is now named for the nearby small town of Sakkara rather than a Cthonic goddess, since no such things exist in my setting.
Then I found myself a quartet of players, and set them loose on it!
Currently I have a Fighter 4, an Explorer 5, a Witch 4, and a Dwarven Machinist 2. They are currently leading 6 henchmen, and have cleared out everything on the first floor of the Temple except Idimmu and his minions. They just had a nasty fight with the Red Eye Gnolls and killed off a rogue Malyn along with an Invisible Stalker he summoned using a one-use amulet. It's notable that between the Machinist and a hench with Alertness, they're doing a surprisingly great job of spotting secret doors and dealing with traps. Also Explorers are completely amazing and every party should have one.
The campaign log and wiki is here: https://chroniclesofazoth.obsidianportal.com/ . The wiki is currently incomplete, lacking quite a lot of setting information I have in text documents, and the characters are out of date (I've had two PC deaths and the players haven't updated their character pages). However the campaign log is complete apart from a run of missed entries last month due to a hideous crunch period at work. I'm steadily expanding the information on the Wiki as time goes on.